PrimePCR™ Probe Assay: ADRA1B, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0030605
Assay Design:   Intron-spanning
Chromosome Location:   5:159344793-159398958question
Amplicon Length:   112
Splice Variants Targeted:   ENST00000306675

Gene Information

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A -1B and -1D all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. [provided by RefSeq Jul 2008]

Gene Symbol:   ADRA1B
Gene Name:   adrenergic, alpha-1B-, receptor
Aliases:   ADRA1, ALPHA1BAR
RefSeq:   NC_000005.9 NT_023133.13
Ensembl:   ENSG00000170214
Entrez:   147
Chromosome Mapping:   5q33.3

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