PrimePCR™ Probe Assay: STAT4, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0031987
Assay Design:   Intron-spanning
Chromosome Location:   2:192011434-192012862question
Amplicon Length:   81
Splice Variants Targeted:   ENST00000358470 ENST00000392320 ENST00000413064 ENST00000409995 ENST00000450994

Gene Information

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors STAT family members are phosphorylated by the receptor associated kinases and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq Aug 2011]

Gene Symbol:   STAT4
Gene Name:   signal transducer and activator of transcription 4
Aliases:   SLEB11
RefSeq:   NC_000002.11 NG_012852.1 NT_005403.17
Ensembl:   ENSG00000138378
Entrez:   6775
Chromosome Mapping:   2q32.2-q32.3

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