PrimePCR™ Probe Assay: IL13, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0032669
Assay Design:   Intron-spanning
Chromosome Location:   5:131995111-131995482question
Amplicon Length:   90
Splice Variants Targeted:   ENST00000304506

Gene Information

This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene IL3 IL5 IL4 and CSF2 form a cytokine gene cluster on chromosome 5q with this gene particularly close to IL4. [provided by RefSeq Jul 2008]

Gene Symbol:   IL13
Gene Name:   interleukin 13
Aliases:   ALRH, BHR1, IL-13, MGC116786, MGC116788, MGC116789, P600
RefSeq:   NC_000005.9 NG_012090.1 NT_034772.6
Ensembl:   ENSG00000169194
Entrez:   3596
Chromosome Mapping:   5q31

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