PrimePCR™ Probe Assay: CPT1A, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0033855
Assay Design:   Intron-spanning
Chromosome Location:   11:68549345-68552368question
Amplicon Length:   139
Splice Variants Targeted:   ENST00000540367 ENST00000538308 ENST00000539743 ENST00000376618 ENST00000265641

Gene Information

The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable) together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   CPT1A
Gene Name:   carnitine palmitoyltransferase 1A (liver)
Aliases:   CPT1, CPT1-L, L-CPT1
RefSeq:   NC_000011.9 NG_011801.1 NT_167190.1
Ensembl:   ENSG00000110090
Entrez:   1374
Chromosome Mapping:   11q13.2

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