PrimePCR™ Probe Assay: CDC25A, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0039439
Assay Design:   Intron-spanning
Chromosome Location:   3:48228193-48229336question
Amplicon Length:   116
Splice Variants Targeted:   ENST00000302506 ENST00000351231 ENST00000443342 ENST00000437972

Gene Information

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   CDC25A
Gene Name:   cell division cycle 25 homolog A (S. pombe)
Aliases:   CDC25A2
RefSeq:   NC_000003.11 NT_022517.18
Ensembl:   ENSG00000164045
Entrez:   993
Chromosome Mapping:   3p21

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