PrimePCR™ Probe Assay: RYR2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0039683
Assay Design:   Intron-spanning
Chromosome Location:   1:237944907-237947059question
Amplicon Length:   95
Splice Variants Targeted:   ENST00000366574 ENST00000360064 ENST00000542537 ENST00000540213 ENST00000542288

Gene Information

This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia. [provided by RefSeq Jul 2008]

Gene Symbol:   RYR2
Gene Name:   ryanodine receptor 2 (cardiac)
Aliases:   ARVC2, ARVD2, VTSIP
RefSeq:   NC_000001.10 NG_008799.1 NT_167186.1
Ensembl:   ENSG00000198626
Entrez:   6262
Chromosome Mapping:   1q43

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