PrimePCR™ Probe Assay: CAMK2B, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: CAMK2B, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: CAMK2B, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0040493
Assay Design:   Intron-spanning
Chromosome Location:   7:44294141-44298508question
Amplicon Length:   74
Splice Variants Targeted:   ENST00000457475 ENST00000421607 ENST00000424197 ENST00000415369 ENST00000395747 ENST00000258682 ENST00000346990 ENST00000347193 ENST00000353625 ENST00000358707 ENST00000440254 ENST00000395749 ENST00000350811

Gene Information

The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha beta gamma and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Eight transcript variants encoding eight distinct isoforms have been identified for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   CAMK2B
Gene Name:   calcium/calmodulin-dependent protein kinase II beta
Aliases:   CAM2, CAMK2, CAMKB, MGC29528
RefSeq:   NC_000007.13 NT_007819.17
Ensembl:   ENSG00000058404
Entrez:   816
Chromosome Mapping:   22q12,7p14.3-p14.1

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