PrimePCR™ Probe Assay: PRLR, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0057883
Assay Design:   Intron-spanning
Chromosome Location:   5:35086328-35089727question
Amplicon Length:   160
Splice Variants Targeted:   ENST00000225174 ENST00000469224 ENST00000394965 ENST00000310271 ENST00000484952 ENST00000493402 ENST00000340124 ENST00000440783 ENST00000231423 ENST00000513753 ENST00000348262 ENST00000382002 ENST00000310101 ENST00000514206 ENST00000509839 ENST00000503330 ENST00000504500 ENST00000542609 ENST00000314888 ENST00000540444

Gene Information

This gene encodes a receptor for the anterior pituitary hormone prolactin and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq Feb 2011]

Gene Symbol:   PRLR
Gene Name:   prolactin receptor
Aliases:   hPRLrI
RefSeq:   NC_000005.9 NT_006576.16
Ensembl:   ENSG00000113494
Entrez:   5618
Chromosome Mapping:   5p13.2

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