PrimePCR™ Probe Assay: EXOSC1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: EXOSC1, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: EXOSC1, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0041581
Assay Design:   exonic
Chromosome Location:   10:99196177-99196271question
Amplicon Length:   65
Splice Variants Targeted:   ENST00000370902 ENST00000370886 ENST00000370885 ENST00000485122 ENST00000477692 ENST00000370884

Gene Information

This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. [provided by RefSeq Jul 2008]

Gene Symbol:   EXOSC1
Gene Name:   exosome component 1
Aliases:   CGI-108, CSL4, Csl4p, SKI4, Ski4p, hCsl4p, p13
RefSeq:   NC_000010.10 NT_030059.13
Ensembl:   ENSG00000171311
Entrez:   51013
Chromosome Mapping:   10q24

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