PrimePCR™ Probe Assay: JAG1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: JAG1, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: JAG1, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0050124
Assay Design:   exonic
Chromosome Location:   20:10639150-10639275question
Amplicon Length:   96
Splice Variants Targeted:   ENST00000254958 ENST00000423891

Gene Information

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1 the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq Jul 2008]

Gene Symbol:   JAG1
Gene Name:   jagged 1
Aliases:   AGS, AHD, AWS, CD339, HJ1, JAGL1, MGC104644
RefSeq:   NC_000020.10 NG_007496.1 NT_011387.8
Ensembl:   ENSG00000101384
Entrez:   182
Chromosome Mapping:   20p12.1-p11.23

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