Gene:  PPARA, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Design and Validation of Real-Time PCR Primers-test
Pathway Curation
and Array Design Strategy
Control and Reference Assays for Real-Time PCR

Peroxisome proliferators include hypolipidemic drugs herbicides leukotriene antagonists and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors called PPARs which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha beta/delta and gamma) have been identified. This gene encodes the subtype PPAR-alpha which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene although the full-length nature of only two has been determined. [provided by RefSeq Jul 2008]

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My PrimePCR Hot List stores your saved PrimePCR products and configurations

My PrimePCR Hot List stores your saved PrimePCR products and configurations

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My PrimePCR Hot List stores your saved PrimePCR products and configurations

My PrimePCR Hot List stores your saved PrimePCR products and configurations

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