PrimePCR™ Probe Assay: BAK1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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PrimePCR™ PreAmp for Probe Assay: BAK1, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: BAK1, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0041364
Assay Design:   exonic
Chromosome Location:   6:33541477-33541681question
Amplicon Length:   175
Splice Variants Targeted:   ENST00000290378 ENST00000374467 ENST00000360661 ENST00000442998

Gene Information

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq Jul 2008]

Gene Symbol:   BAK1
Gene Name:   BCL2-antagonist/killer 1
Aliases:   BAK, BAK-LIKE, BCL2L7, CDN1, MGC117255, MGC3887
RefSeq:   NC_000006.11 NT_007592.15
Ensembl:   ENSG00000030110
Entrez:   578
Chromosome Mapping:   6p21.3

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