PrimePCR™ Probe Assay: SRC, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0055418
Assay Design:   exonic
Chromosome Location:   20:36033550-36033686question
Amplicon Length:   107
Splice Variants Targeted:   ENST00000373578 ENST00000373567 ENST00000373558 ENST00000445403 ENST00000360723 ENST00000358208

Gene Information

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   SRC
Gene Name:   v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
Aliases:   ASV, SRC1, c-SRC, p60-Src
RefSeq:   NC_000020.10 NG_023033.1 NT_011362.10
Ensembl:   ENSG00000197122
Entrez:   6714
Chromosome Mapping:   20q12-q13

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