PrimePCR™ Probe Assay: SUFU, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: SUFU, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: SUFU, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0058238
Assay Design:   exonic
Chromosome Location:   10:104269049-104309863question
Amplicon Length:   119
Splice Variants Targeted:   ENST00000369902 ENST00000369899 ENST00000423559

Gene Information

The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.[provided by RefSeq May 2010]

Gene Symbol:   SUFU
Gene Name:   suppressor of fused homolog (Drosophila)
Aliases:   PRO1280, SUFUH, SUFUXL
RefSeq:   NG_011901.1 NC_000010.10 NT_030059.13 NG_021338.1
Ensembl:   ENSG00000107882
Entrez:   51684
Chromosome Mapping:   10q24.32

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