PrimePCR™ Probe Assay: FGF3, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: FGF3, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: FGF3, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0029355
Assay Design:   Intron-spanning
Chromosome Location:   11:69625322-69631156question
Amplicon Length:   186
Splice Variants Targeted:   ENST00000334134

Gene Information

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development cell growth morphogenesis tissue repair tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2 a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation. [provided by RefSeq Jul 2008]

Gene Symbol:   FGF3
Gene Name:   fibroblast growth factor 3
Aliases:   HBGF-3, INT2
RefSeq:   NC_000011.9 NG_009016.1 NT_167190.1
Ensembl:   ENSG00000186895
Entrez:   2248
Chromosome Mapping:   11q13

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