PrimePCR™ Probe Assay: SCNN1B, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: SCNN1B, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: SCNN1B, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0031046
Assay Design:   Intron-spanning
Chromosome Location:   16:23360114-23364170question
Amplicon Length:   137
Splice Variants Targeted:   ENST00000343070 ENST00000307331

Gene Information

Nonvoltage-gated amiloride-sensitive sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha beta and gamma. This gene encodes the beta subunit and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1) and Liddle syndrome. [provided by RefSeq Apr 2009]

Gene Symbol:   SCNN1B
Gene Name:   sodium channel, nonvoltage-gated 1, beta
Aliases:   BESC1, ENaCb, ENaCbeta, SCNEB
RefSeq:   NC_000016.9 NG_011908.1 NT_010393.16
Ensembl:   ENSG00000168447
Entrez:   6338
Chromosome Mapping:   16p12.2-p12.1

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