PrimePCR™ Probe Assay: TP73, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0026199
Assay Design:   Intron-spanning
Chromosome Location:   1:3639949-3643754question
Amplicon Length:   131
Splice Variants Targeted:   ENST00000378295 ENST00000354437 ENST00000378288 ENST00000378285 ENST00000378280 ENST00000357733 ENST00000346387 ENST00000378290

Gene Information

This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele) supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene but the biological validity and the full-length nature of some variants have not been determined. [provided by RefSeq Feb 2011]

Gene Symbol:   TP73
Gene Name:   tumor protein p73
Aliases:   P73
RefSeq:   NC_000001.10 NT_004350.19 NG_017035.1
Ensembl:   ENSG00000078900
Entrez:   7161
Chromosome Mapping:   1p36.3

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