PrimePCR™ Probe Assay: DPYD, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0026939
Assay Design:   Intron-spanning
Chromosome Location:   1:98187143-98206029question
Amplicon Length:   137
Splice Variants Targeted:   ENST00000370192 ENST00000306031 ENST00000423006

Gene Information

The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq May 2009]

Gene Symbol:   DPYD
Gene Name:   dihydropyrimidine dehydrogenase
Aliases:   DHP, DHPDHASE, DPD, MGC132008, MGC70799
RefSeq:   NC_000001.10 NG_008807.1 NT_032977.9
Ensembl:   ENSG00000188641
Entrez:   1806
Chromosome Mapping:   1p22

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