PrimePCR™ Probe Assay: SERPING1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: SERPING1, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: SERPING1, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0052700
Assay Design:   exonic
Chromosome Location:   11:57367367-57367456question
Amplicon Length:   60
Splice Variants Targeted:   ENST00000405496 ENST00000278407 ENST00000457869 ENST00000340687 ENST00000378323 ENST00000378324 ENST00000403558

Gene Information

This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform. [provided by RefSeq Jul 2008]

Gene Symbol:   SERPING1
Gene Name:   serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
Aliases:   C1IN, C1INH, C1NH, HAE1, HAE2
RefSeq:   NC_000011.9 NG_009625.1 NT_167190.1
Ensembl:   ENSG00000149131
Entrez:   710
Chromosome Mapping:   11q12-q13.1

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