PrimePCR™ Probe Assay: NTRK2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0052656
Assay Design:   exonic
Chromosome Location:   9:87342637-87342751question
Amplicon Length:   85
Splice Variants Targeted:   ENST00000376208 ENST00000304053 ENST00000277120 ENST00000323115 ENST00000359847 ENST00000376214 ENST00000376213 ENST00000395882 ENST00000395866

Gene Information

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that upon neurotrophin binding phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   NTRK2
Gene Name:   neurotrophic tyrosine kinase, receptor, type 2
Aliases:   GP145-TrkB, TRKB
RefSeq:   NC_000009.11 NT_008470.19 NG_012201.1
Ensembl:   ENSG00000148053
Entrez:   4915
Chromosome Mapping:   9q22.1

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