PrimePCR™ Probe Assay: DES, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: DES, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: DES, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0054348
Assay Design:   exonic
Chromosome Location:   2:220285251-220285362question
Amplicon Length:   82
Splice Variants Targeted:   ENST00000373960

Gene Information

This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy a familial cardiac and skeletal myopathy (CSM) and with distal myopathies. [provided by RefSeq Jul 2008]

Gene Symbol:   DES
Gene Name:   desmin
Aliases:   CMD1I, CSM1, CSM2, FLJ12025, FLJ39719, FLJ41013, FLJ41793
RefSeq:   NC_000002.11 NG_008043.1 NT_005403.17
Ensembl:   ENSG00000175084
Entrez:   1674
Chromosome Mapping:   2q35

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