PrimePCR™ Probe Assay: TNFRSF4, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: TNFRSF4, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: TNFRSF4, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0055125
Assay Design:   exonic
Chromosome Location:   1:1147359-1147487question
Amplicon Length:   99
Splice Variants Targeted:   ENST00000598504 ENST00000544886 ENST00000373409 ENST00000499247 ENST00000268957 ENST00000259053 ENST00000504830 ENST00000352040 ENST00000379236 ENST00000311127 ENST00000458420 ENST00000261381

Gene Information

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq Jul 2008]

Gene Symbol:   TNFRSF4
Gene Name:   tumor necrosis factor receptor superfamily, member 4
Aliases:   ACT35, CD134, OX40, TXGP1L
RefSeq:   NC_000001.10 NT_004350.19
Ensembl:   ENSG00000186827
Entrez:   7293
Chromosome Mapping:   1p36

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