PrimePCR™ Probe Assay: GJA1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0028675
Assay Design:   Intron-spanning
Chromosome Location:   6:121756921-121768079question
Amplicon Length:   130
Splice Variants Targeted:   ENST00000282561

Gene Information

This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia and heart malformations. [provided by RefSeq Jul 2008]

Gene Symbol:   GJA1
Gene Name:   gap junction protein, alpha 1, 43kDa
Aliases:   CX43, DFNB38, GJAL, HSS, ODDD
RefSeq:   NC_000006.11 NG_008308.1 NT_025741.15
Ensembl:   ENSG00000152661
Entrez:   2697
Chromosome Mapping:   6q21-q23.2

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