PrimePCR™ Probe Assay: C4BPA, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: C4BPA, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: C4BPA, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0051265
Assay Design:   exonic
Chromosome Location:   1:207287446-207287595question
Amplicon Length:   120
Splice Variants Targeted:   ENST00000367070 ENST00000421786

Gene Information

This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. Along with a single unique beta-chain seven identical alpha-chains encoded by this gene assemble into the predominant isoform of C4b-binding protein a multimeric protein that controls activation of the complement cascade through the classical pathway. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Two pseudogenes of this gene are also found in the cluster. [provided by RefSeq Jul 2008]

Gene Symbol:   C4BPA
Gene Name:   complement component 4 binding protein, alpha
Aliases:   C4BP, PRP
RefSeq:   NC_000001.10 NT_167186.1
Ensembl:   ENSG00000123838
Entrez:   722
Chromosome Mapping:   1q32

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