PrimePCR™ Probe Assay: MBL2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: MBL2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: MBL2, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0053565
Assay Design:   exonic
Chromosome Location:   10:54525835-54525949question
Amplicon Length:   85
Splice Variants Targeted:   ENST00000373968

Gene Information

This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. [provided by RefSeq Jul 2008]

Gene Symbol:   MBL2
Gene Name:   mannose-binding lectin (protein C) 2, soluble
Aliases:   COLEC1, HSMBPC, MBL, MBP, MBP1, MGC116832, MGC116833
RefSeq:   NC_000010.10 NG_008196.1 NT_030059.13
Ensembl:   ENSG00000165471
Entrez:   4153
Chromosome Mapping:   10q11.2

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