PrimePCR™ Probe Assay: PDE1C, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: PDE1C, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: PDE1C, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0052907
Assay Design:   exonic
Chromosome Location:   7:31918635-31918783question
Amplicon Length:   119
Splice Variants Targeted:   ENST00000396193 ENST00000396191 ENST00000321453 ENST00000396184 ENST00000396182

Gene Information

Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family such as PDE1C are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al. 1992 [PubMed 1326532]).[supplied by OMIM Oct 2009]

Gene Symbol:   PDE1C
Gene Name:   phosphodiesterase 1C, calmodulin-dependent 70kDa
Aliases:   Hcam3
RefSeq:   NC_000007.13 NT_007819.17
Ensembl:   ENSG00000154678
Entrez:   5137
Chromosome Mapping:   7p14.3

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