PrimePCR™ Probe Assay: SOD2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0039142
Assay Design:   exonic
Chromosome Location:   6:160113711-160113843question
Amplicon Length:   103
Splice Variants Targeted:   ENST00000367055 ENST00000538183 ENST00000367054 ENST00000546087 ENST00000444946 ENST00000337404 ENST00000545162 ENST00000535561 ENST00000537657 ENST00000401980 ENST00000452684

Gene Information

This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC) premature aging sporadic motor neuron disease and cancer. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq Jul 2008]

Gene Symbol:   SOD2
Gene Name:   superoxide dismutase 2, mitochondrial
Aliases:   IPOB, MNSOD, MVCD6
RefSeq:   NC_000006.11 NT_025741.15 NG_008729.1
Ensembl:   ENSG00000112096
Entrez:   6648
Chromosome Mapping:   6q25.3

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