PrimePCR™ Probe Assay: IGFBP3, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0027746
Assay Design:   Intron-spanning
Chromosome Location:   7:45956199-45956877question
Amplicon Length:   104
Splice Variants Targeted:   ENST00000275521 ENST00000381086 ENST00000381083 ENST00000428530 ENST00000417621 ENST00000448817 ENST00000438491 ENST00000545032 ENST00000442142 ENST00000433047

Gene Information

This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form it circulates in the plasma prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq Jul 2008]

Gene Symbol:   IGFBP3
Gene Name:   insulin-like growth factor binding protein 3
Aliases:   BP-53, IBP3
RefSeq:   NC_000007.13 NT_007819.17 NG_011508.1
Ensembl:   ENSG00000146674
Entrez:   3486
Chromosome Mapping:   7p13-p12

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