PrimePCR™ Probe Assay: SET, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0041403
Assay Design:   exonic
Chromosome Location:   9:131456920-131457032question
Amplicon Length:   83
Splice Variants Targeted:   ENST00000339554 ENST00000371482 ENST00000371475 ENST00000265663 ENST00000437259 ENST00000392812 ENST00000371474 ENST00000371473 ENST00000541195 ENST00000502935 ENST00000369680 ENST00000393583 ENST00000296440 ENST00000358536 ENST00000372692 ENST00000409104 ENST00000322030 ENST00000372686 ENST00000372688

Gene Information

The protein encoded by this gene inhibits acetylation of nucleosomes especially histone H4 by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Oct 2011]

Gene Symbol:   SET
Gene Name:   SET nuclear oncogene
Aliases:   2PP2A, I2PP2A, IGAAD, IPP2A2, PHAPII, TAF-I, TAF-IBETA
RefSeq:   NC_000009.11 NT_008470.19
Ensembl:   ENSG00000119335
Entrez:   6418
Chromosome Mapping:   9q34

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