PrimePCR™ Probe Assay: CASP6, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0027023
Assay Design:   Intron-spanning
Chromosome Location:   4:110610664-110612107question
Amplicon Length:   133
Splice Variants Targeted:   ENST00000352981 ENST00000265164

Gene Information

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits large and small that dimerize to form the active enzyme. This protein is processed by caspases 7 8 and 10 and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. [provided by RefSeq Jul 2008]

Gene Symbol:   CASP6
Gene Name:   caspase 6, apoptosis-related cysteine peptidase
Aliases:   MCH2
RefSeq:   NC_000004.11 NT_016354.19
Ensembl:   ENSG00000138794
Entrez:   839
Chromosome Mapping:   4q25

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