PrimePCR™ Probe Assay: NFATC2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: NFATC2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: NFATC2, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0027173
Assay Design:   Intron-spanning
Chromosome Location:   20:50071147-50090574question
Amplicon Length:   107
Splice Variants Targeted:   ENST00000371564 ENST00000396009 ENST00000414705

Gene Information

This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq Jul 2008]

Gene Symbol:   NFATC2
Gene Name:   nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
Aliases:   NFAT1, NFATP
RefSeq:   NC_000020.10 NT_011362.10
Ensembl:   ENSG00000101096
Entrez:   4773
Chromosome Mapping:   20q13.2

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