PrimePCR™ Probe Assay: Myc, Rat

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qRnoCIP0029591
Assay Design:   intron_spanning
Chromosome Location:   7:103160322-103161438question
Amplicon Length:   88
Splice Variants Targeted:   ENSRNOT00000006188

Gene Information

The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma, in human. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini, in human and mouse. Rat mRNA also has a similarly placed CUG upstream of the AUG start site, suggesting that it may also produce two Myc proteins. [provided by RefSeq, Jul 2008]

Gene Symbol:   Myc
Gene Name:   Myc proto-oncogene protein
Aliases:   Not Available
RefSeq:   NM_012603
Ensembl:   ENSRNOG00000004500
Entrez:   24577
Chromosome Mapping:   7q33

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