Gene:  WASL, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Lookup Tool
Design and Validation of Real-Time PCR Primers-test
Pathway Curation
and Array Design Strategy
Control and Reference Assays for Real-Time PCR

The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli and interact with multiple proteins. Recent studies have demonstrated that these proteins directly or indirectly associate with the small GTPase Cdc42 known to regulate formation of actin filaments and the cytoskeletal organizing complex Arp2/3. The WASL gene product is a homolog of WAS protein however unlike the latter it is ubiquitously expressed and shows highest expression in neural tissues. It has been shown to bind Cdc42 directly and induce formation of long actin microspikes. [provided by RefSeq Jul 2008]

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My PrimePCR Hot List stores your saved PrimePCR products and configurations

My PrimePCR Hot List stores your saved PrimePCR products and configurations

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My PrimePCR Hot List stores your saved PrimePCR products and configurations

My PrimePCR Hot List stores your saved PrimePCR products and configurations

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My PrimePCR Hot List stores your saved PrimePCR products and configurations

My PrimePCR Hot List stores your saved PrimePCR products and configurations

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