PrimePCR™ Probe Assay: KCNN4, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0026168
Assay Design:   Intron-spanning
Chromosome Location:   19:44271755-44273146question
Amplicon Length:   107
Splice Variants Targeted:   ENST00000262888 ENST00000407385

Gene Information

The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes but it differs enough to possibly be considered as part of a new subfamily. [provided by RefSeq Jul 2008]

Gene Symbol:   KCNN4
Gene Name:   potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
Aliases:   IK1, IKCA1, KCA4, KCa3.1, SK4, hIKCa1, hKCa4, hSK4
RefSeq:   NC_000019.9 NT_011109.16
Ensembl:   ENSG00000104783
Entrez:   3783
Chromosome Mapping:   19q13.2

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