PrimePCR™ Probe Assay: Abcc9, Mouse

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qMmuCEP0055265
Assay Design:   exonic
Chromosome Location:   6:142682910-142685010question
Amplicon Length:   89
Splice Variants Targeted:   ENSMUST00000100827 ENSMUST00000087527 ENSMUST00000111771 ENSMUST00000073173

Gene Information

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1 MDR/TAP MRP ALD OABP GCN20 White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The human protein is thought to form ATP-sensitive potassium channels in cardiac skeletal and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extrapancreatic ATP-sensitive potassium channels. Alternative splicing of this gene results in four known transcript variants and several other variants that have not yet been fully described. [provided by RefSeq Jul 2008]

Gene Symbol:   Abcc9
Gene Name:   ATP-binding cassette, sub-family C (CFTR/MRP), member 9
Aliases:   AI414027, AI449286, SUR2A, SUR2B, Sur2
RefSeq:   NC_000072.6 NT_039360.8
Ensembl:   ENSMUSG00000030249
Entrez:   20928
Chromosome Mapping:   6 G2|6 70.0 cM

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