PrimePCR™ Probe Assay: ARG1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0051047
Assay Design:   exonic
Chromosome Location:   6:131905303-131905429question
Amplicon Length:   97
Splice Variants Targeted:   ENST00000476845 ENST00000356962 ENST00000368087

Gene Information

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution subcellular localization immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Sep 2011]

Gene Symbol:   ARG1
Gene Name:   arginase, liver
Aliases:   Not Available
RefSeq:   NC_000006.11 NG_007086.2 NT_025741.15
Ensembl:   ENSG00000118520
Entrez:   383
Chromosome Mapping:   6q23

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