PrimePCR™ Probe Assay: NFE2L2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: NFE2L2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: NFE2L2, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0041265
Assay Design:   exonic
Chromosome Location:   2:178098902-178129264question
Amplicon Length:   72
Splice Variants Targeted:   ENST00000397063 ENST00000397062 ENST00000446151 ENST00000464747 ENST00000449627 ENST00000448782 ENST00000586532 ENST00000421929 ENST00000423513 ENST00000588123

Gene Information

This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jan 2012]

Gene Symbol:   NFE2L2
Gene Name:   nuclear factor (erythroid-derived 2)-like 2
Aliases:   NRF2
RefSeq:   NC_000002.11 NT_005403.17
Ensembl:   ENSG00000116044
Entrez:   4780
Chromosome Mapping:   2q31

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