PrimePCR™ Probe Assay: LGALS3, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: LGALS3, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: LGALS3, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0051678
Assay Design:   exonic
Chromosome Location:   14:55607059-55609377question
Amplicon Length:   69
Splice Variants Targeted:   ENST00000254301 ENST00000554715

Gene Information

This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis innate immunity cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.[provided by RefSeq Apr 2010]

Gene Symbol:   LGALS3
Gene Name:   lectin, galactoside-binding, soluble, 3
Aliases:   CBP35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2
RefSeq:   NC_000014.8 NT_026437.12 NG_017089.1
Ensembl:   ENSG00000131981
Entrez:   3958
Chromosome Mapping:   14q22.3

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