PrimePCR™ Probe Assay: S1pr1, Mouse

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: S1pr1, Mouse
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: S1pr1, Mouse
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qMmuCEP0058526
Assay Design:   exonic
Chromosome Location:   3:115711976-115712072question
Amplicon Length:   67
Splice Variants Targeted:   ENSMUST00000055676

Gene Information

This gene encodes a G-protein-coupled receptor bound by the lysophospholipid sphingosine 1-phosphate. The gene product functions in endothelial cells and is involved in vascular and heart development. This receptor is highly expressed in T and B lymphocytes and it plays a role in T cell and B cell export from peripheral lymphoid organs. This protein is bound and downregulated by FTY720 an exogenous immunosuppressant drug studied in mouse disease models for multiple sclerosis in humans. [provided by RefSeq Jan 2010]

Gene Symbol:   S1pr1
Gene Name:   Sphingosine-1-phosphate receptor 1
Aliases:   AI849002, Edg1, Lpb1, S1p, S1p1
RefSeq:   NC_000069.6 NT_039240.8
Ensembl:   ENSMUSG00000045092
Entrez:   13609
Chromosome Mapping:   3 G1|3

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