PrimePCR™ Probe Assay: REL, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0053286
Assay Design:   exonic
Chromosome Location:   2:61149284-61149419question
Amplicon Length:   106
Splice Variants Targeted:   ENST00000295025 ENST00000394479

Gene Information

The REL gene encodes c-Rel a transcription factor that is a member of the Rel/NFKB family which also includes RELA (MIM 164014) RELB (604758) NFKB1 (MIM 164011) and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain' which is responsible for DNA binding dimerization nuclear localization and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein 2007 [PubMed 18037997]).[supplied by OMIM May 2008]

Gene Symbol:   REL
Gene Name:   v-rel reticuloendotheliosis viral oncogene homolog (avian)
Aliases:   C-Rel
RefSeq:   NC_000002.11 NT_022184.15
Ensembl:   ENSG00000162924
Entrez:   5966
Chromosome Mapping:   2p13-p12

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