PrimePCR™ Probe Assay: PCK2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0026183
Assay Design:   Intron-spanning
Chromosome Location:   14:24566244-24567484question
Amplicon Length:   146
Splice Variants Targeted:   ENST00000216780 ENST00000396973 ENST00000545054

Gene Information

This gene encodes a member of the phosphoenolpyruvate carboxykinase (GTP) family. The protein is a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of GTP. A cytosolic form encoded by a different gene has also been characterized and is the key enzyme of gluconeogenesis in the liver. The encoded protein may serve a similar function although it is constitutively expressed and not modulated by hormones such as glucagon and insulin that regulate the cytosolic form. Alternatively spliced transcript variants have been described. [provided by RefSeq Jul 2008]

Gene Symbol:   PCK2
Gene Name:   phosphoenolpyruvate carboxykinase 2 (mitochondrial)
Aliases:   PEPCK, PEPCK-M, PEPCK2
RefSeq:   NC_000014.8 NT_026437.12 NG_008162.1
Ensembl:   ENSG00000100889
Entrez:   5106
Chromosome Mapping:   14q11.2

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