PrimePCR™ Probe Assay: SCNN1A, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0024081
Assay Design:   Exonic
Chromosome Location:   12:6456234-6456400question
Amplicon Length:   137
Splice Variants Targeted:   ENST00000360168 ENST00000540037 ENST00000228916 ENST00000358945

Gene Information

Nonvoltage-gated amiloride-sensitive sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha beta and gamma. This gene encodes the alpha subunit and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1) a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq Apr 2009]

Gene Symbol:   SCNN1A
Gene Name:   sodium channel, nonvoltage-gated 1 alpha
Aliases:   BESC2, ENaCa, ENaCalpha, FLJ21883, SCNEA, SCNN1
RefSeq:   NC_000012.11 NG_007506.1 NG_011945.1 NT_009759.16
Ensembl:   ENSG00000111319
Entrez:   6337
Chromosome Mapping:   12p13

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