PrimePCR™ Probe Assay: FPGS, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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PrimePCR™ PreAmp for Probe Assay: FPGS, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: FPGS, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0024210
Assay Design:   Exonic
Chromosome Location:   9:130569869-130570524question
Amplicon Length:   80
Splice Variants Targeted:   ENST00000373247 ENST00000373228 ENST00000373225 ENST00000431857 ENST00000423577 ENST00000393706 ENST00000373245

Gene Information

This gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and therefore is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. While several transcript variants may exist for this gene the full-length natures of only two have been biologically validated to date. These two variants encode distinct isoforms. [provided by RefSeq Jul 2008]

Gene Symbol:   FPGS
Gene Name:   folylpolyglutamate synthase
Aliases:   Not Available
RefSeq:   NC_000009.11 NG_009551.1 NT_008470.19 NG_023245.1
Ensembl:   ENSG00000136877
Entrez:   2356
Chromosome Mapping:   9q34.1

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