PrimePCR™ Probe Assay: CXCR4, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: CXCR4, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: CXCR4, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0024247
Assay Design:   Exonic
Chromosome Location:   2:136872596-136872767question
Amplicon Length:   142
Splice Variants Targeted:   ENST00000409817 ENST00000241393 ENST00000537957

Gene Information

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts hypogammaglobulinemia infections and myelokathexis) syndrome. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq Jul 2008]

Gene Symbol:   CXCR4
Gene Name:   chemokine (C-X-C motif) receptor 4
Aliases:   CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM
RefSeq:   NC_000002.11 NT_022135.16 NG_011587.1
Ensembl:   ENSG00000121966
Entrez:   7852
Chromosome Mapping:   2q21

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