PrimePCR™ Probe Assay: MST1R, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: MST1R, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: MST1R, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0025015
Assay Design:   Exonic
Chromosome Location:   3:49932626-49932771question
Amplicon Length:   116
Splice Variants Targeted:   ENST00000440292 ENST00000344206 ENST00000296474

Gene Information

This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung and together with MSP thought to be involved in host defense. Alternatively spliced transcript variants encoding different isoforms with different structural and biochemical properties have been described (PMID:8816464). [provided by RefSeq Oct 2011]

Gene Symbol:   MST1R
Gene Name:   macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
Aliases:   CD136, CDw136, PTK8, RON
RefSeq:   NC_000003.11 NT_022517.18
Ensembl:   ENSG00000164078
Entrez:   4486
Chromosome Mapping:   3p21.3

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