PrimePCR™ Probe Assay: TNNC1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0025562
Assay Design:   Exonic
Chromosome Location:   3:52485765-52485860question
Amplicon Length:   66
Splice Variants Targeted:   ENST00000232975 ENST00000496590

Gene Information

Troponin is a central regulatory protein of striated muscle contraction and together with tropomyosin is located on the actin filament. Troponin consists of 3 subunits: TnI which is the inhibitor of actomyosin ATPase; TnT which contains the binding site for tropomyosin; and TnC the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI thus allowing the interaction of actin with myosin the hydrolysis of ATP and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq Oct 2008]

Gene Symbol:   TNNC1
Gene Name:   troponin C type 1 (slow)
Aliases:   CMD1Z, CMH13, TN-C, TNC, TNNC
RefSeq:   NC_000003.11 NG_008963.1 NT_022517.18
Ensembl:   ENSG00000114854
Entrez:   7134
Chromosome Mapping:   3p21.1

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