PrimePCR™ Probe Assay: RIPK3, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0025866
Assay Design:   Exonic
Chromosome Location:   14:24805514-24806107question
Amplicon Length:   74
Splice Variants Targeted:   ENST00000216274

Gene Information

The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq Jul 2008]

Gene Symbol:   RIPK3
Gene Name:   receptor-interacting serine-threonine kinase 3
Aliases:   RIP3
RefSeq:   NC_000014.8 NT_026437.12
Ensembl:   ENSG00000129465
Entrez:   11035
Chromosome Mapping:   14q11.2

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