PrimePCR™ Probe Assay: CHRM4, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: CHRM4, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: CHRM4, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0032003
Assay Design:   Exonic
Chromosome Location:   11:46407027-46407123question
Amplicon Length:   67
Splice Variants Targeted:   ENST00000433765

Gene Information

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition phosphoinositide degeneration and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however mouse studies link its function to adenylyl cyclase inhibition. [provided by RefSeq Jul 2008]

Gene Symbol:   CHRM4
Gene Name:   cholinergic receptor, muscarinic 4
Aliases:   HM4, M4R
RefSeq:   NC_000011.9 NT_009237.18
Ensembl:   ENSG00000180720
Entrez:   1132
Chromosome Mapping:   11p12-p11.2

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