PrimePCR™ Probe Assay: ATP5G1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0035876
Assay Design:   Exonic
Chromosome Location:   17:46973101-9882225question
Amplicon Length:   112
Splice Variants Targeted:   ENST00000355938 ENST00000503641 ENST00000393366 ENST00000506855

Gene Information

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core F1 and the membrane-spanning component Fo comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha beta gamma delta and epsilon) assembled with a stoichiometry of 3 alpha 3 beta and a single representative of the other 3. The proton channel seems to have nine subunits (a b c d e f g F6 and 8). This gene is one of three genes that encode subunit c of the proton channel. Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq Jul 2008]

Gene Symbol:   ATP5G1
Gene Name:   ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
Aliases:   ATP5A, ATP5G
RefSeq:   NC_000017.10 NT_010783.15
Ensembl:   ENSG00000159199
Entrez:   516
Chromosome Mapping:   17q21.32

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