PrimePCR™ Probe Assay: PSMA4, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0039031
Assay Design:   exonic
Chromosome Location:   15:78837976-78838072question
Amplicon Length:   67
Splice Variants Targeted:   ENST00000560217 ENST00000044462 ENST00000559082 ENST00000559948 ENST00000413382 ENST00000559146 ENST00000558281 ENST00000559365 ENST00000559437 ENST00000560737 ENST00000559154 ENST00000558094

Gene Information

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome the immunoproteasome is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   PSMA4
Gene Name:   proteasome (prosome, macropain) subunit, alpha type, 4
Aliases:   HC9, HsT17706, MGC111191, MGC12467, MGC24813, PSC9
RefSeq:   NC_000015.9 NT_010194.17
Ensembl:   ENSG00000041357
Entrez:   5685
Chromosome Mapping:   15q25.1

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